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Gamma Interferon Does Not Enhance Clearance ofPseudomonas aeruginosabut Does Amplify a Proinflammatory Response in a Murine Model of Postseptic Immunosuppression

23 Nov 2004

Abstract excerpt

Patients that have suffered a major injury may sustain a period of immunocompromise and altered Th1/Th2 cytokine balance that can predispose them to opportunistic infections. Pseudomonas aeruginosa is frequently a causative organism for nosocomial infections in critically ill patients and is associated with high mortality. We previously mimicked this clinical scenario by challenging mice with P. aeruginosa 5 days...

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PMID: 15557610
DOI: 10.1128/iai.72.12.6892-6901.2004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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