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Article

Mice Lacking γδ T Cells Exhibit Impaired Clearance of Pseudomonas aeruginosa Lung Infection and Excessive Production of Inflammatory Cytokines.

Infection and immunity - 20 May 2020

Omar Toka, Ziltener Pascal, Chamberlain Erin, Cheng Zhenyu, Johnston Brent

Abstract excerpt

Pseudomonas aeruginosa is an opportunistic pathogen that causes chronic and life-threatening infections in immunocompromised patients. A better understanding of the role that innate immunity plays in the control of P. aeruginosa infection is crucial for therapeutic development. Specifically, the role of unconventional immune cells like γδ T cells in the clearance of P. aeruginosa lung infection is not yet well...

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Identifiers

PMID: 32229615
DOI: 10.1128/IAI.00171-20
PMCID: PMC7240087

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