Selection on codon usage for error minimization at the protein level.

doi:10.1007/s00239-004-2634-7

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Article

Selection on codon usage for error minimization at the protein level.

Journal of molecular evolution - 1 Sept 2004

Archetti Marco

Abstract excerpt

Given the structure of the genetic code, synonymous codons differ in their capacity to minimize the effects of errors due to mutation or mistranslation. I suggest that this may lead, in protein-coding genes, to a preference for codons that minimize the impact of errors at the protein level. I dev...

Topics

Amino Acids
Animals
Base Composition
Codon
Drosophila melanogaster
Evolution, Molecular
Genetic Code
Models, Genetic
Mutation
Proteins
Rodentia
Selection, Genetic

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