Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Do universal codon-usage patterns minimize the effects of mutation and translation error?

Genome biology - 1 Jan 2005

Marquez Roberto, Smit Sandra, Knight Rob

Abstract excerpt

BACKGROUND: Do species use codons that reduce the impact of errors in translation or replication? The genetic code is arranged in a way that minimizes errors, defined as the sum of the differences in amino-acid properties caused by single-base changes from each codon to each other codon. However, the extent to which organisms optimize the genetic messages written in this code has been far less studied. We tested...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Composition
Share to Codon
Share to Computational Biology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Evolution, Molecular

Share to Genetic Code

Share to Mutation

Share to Protein Biosynthesis

Source

Open in PubMed Open full text

Identifiers

PMID: 16277746
DOI: 10.1186/gb-2005-6-11-r91
PMCID: PMC1297647

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Do universal codon-usage patterns minimize the effects of mutation and translation error?PMID 16277746Read ↗

A simple model based on mutation and selection explains trends in codon and amino-acid usage and GC composition within and across genomes.Semantic proximity Read ↗

Selection on codon usage for error minimization at the protein level.Semantic proximity Read ↗

Variation in global codon usage bias among prokaryotic organisms is associated with their lifestyles.Semantic proximity Read ↗

Codon usage bias and mutation constraints reduce the level of error minimization of the genetic code.Semantic proximity Read ↗

Codon Usage Optimization in the Prokaryotic Tree of Life: How Synonymous Codons Are Differentially Selected in Sequence Domains with Different Expression Levels and Degrees of Conservation.Semantic proximity Read ↗

Codon usage bias from tRNA's point of view: redundancy, specialization, and efficient decoding for translation optimization.Semantic proximity Read ↗

Enhanced effective codon numbers to understand codon usage bias.Semantic proximity Read ↗

Species-specific codon context rules unveil non-neutrality effects of synonymous mutations.Semantic proximity Read ↗

Effect of correlated tRNA abundances on translation errors and evolution of codon usage bias.Semantic proximity Read ↗

Coevolution between Stop Codon Usage and Release Factors in Bacterial Species.Semantic proximity Read ↗

Codon usage bias in prokaryotic genomes and environmental adaptationSemantic proximity Read ↗

Codon usage in mitochondrial genomes: distinguishing context-dependent mutation from translational selection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.