Article
Adapter protein 14-3-3 is required for a presynaptic form of LTP in the cerebellum.
Nature neuroscience - 1 Dec 2004
Simsek-Duran Fatma, Linden David J, Lonart György
Abstract excerpt
Long-term potentiation (LTP) of granule cell-Purkinje cell synapses in the mouse cerebellum requires phosphorylation by protein kinase A of the active-zone protein RIM1alpha at Ser413. Here, we show that the adapter protein 14-3-3 readily binds phosphorylated Ser413 in RIM1alpha, and that presyna...
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