Article
The cerebellum-specific Munc13 isoform Munc13-3 regulates cerebellar synaptic transmission and motor learning in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Jan 2001
Augustin I, Korte S, Rickmann M, Kretzschmar H A, Südhof T C, Herms J W, Brose N
Abstract excerpt
Munc13 proteins form a family of three, primarily brain-specific phorbol ester receptors (Munc13-1/2/3) in mammals. Munc13-1 is a component of presynaptic active zones in which it acts as an essential synaptic vesicle priming protein. In contrast to Munc13-1, which is present in most neurons throughout the rat and mouse CNS, Munc13-3 is almost exclusively expressed in the cerebellum. Munc13-3 mRNA is present in...
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