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Article

Interaction between cardiac sympathetic drive and heart rate in heart failure: modulation by adrenergic receptor genotype.

Journal of the American College of Cardiology - 16 Nov 2004

Kaye David M, Smirk Belinda, Finch Samara, Williams Carolyn, Esler Murray D

Abstract excerpt

OBJECTIVES: In the present study, we aimed to evaluate the effect of adrenergic receptor polymorphisms on the response of myocardium to measured levels of cardiac adrenergic drive, and to evaluate whether polymorphisms of presynaptic adrenoceptors modified the rate of cardiac and systemic release of norepinephrine. BACKGROUND: Heightened sympathetic activity plays an important pathophysiologic role in congestive...

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Identifiers

PMID: 15542284
DOI: 10.1016/j.jacc.2004.07.058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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