Article
Beta2-adrenergic receptor genotype and pulmonary function in patients with heart failure.
Chest - 1 Nov 2006
Snyder Eric M, Turner Stephen T, Johnson Bruce D
Abstract excerpt
OBJECTIVE: Chronic heart failure (CHF) is associated with neurohumoral activation and decrements in pulmonary function (PF). The beta2-adrenergic receptor (ADRB2) modulates airway smooth muscle tone and influences lung fluid clearance. Common polymorphisms of the ADRB2 are associated with differences in ADRB2 function and therefore could differentially influence PF in patients with CHF. METHODS: We studied...
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