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Article

Decreased tumorigenicity of c-Myc-transformed fibroblasts expressing active USF2.

Experimental cell research - 1 Jan 2005

Choe Chungyoul, Chen Nanyue, Sawadogo Michèle

Abstract excerpt

USF is a small family of basic helix-loop-helix leucine zipper (bHLH-zip) transcription factors with DNA binding specificities similar to that of the c-Myc oncoprotein. Evidence for a role of USF in growth control includes inhibition of c-Myc-dependent cellular transformation in vitro and loss of USF transcriptional activity in many cancer cell lines. However, a direct effect of USF on the tumorigenicity of an...

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Identifiers

PMID: 15541720
DOI: 10.1016/j.yexcr.2004.08.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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