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Article

Elevated expression of Ets2 or distinct portions of Ets2 can reverse Ras-mediated cellular transformation.

The Journal of biological chemistry - 24 Jul 1998

Foos G, García-Ramírez J J, Galang C K, Hauser C A

Abstract excerpt

Ets transcription factors are important downstream targets of oncogenic Ras. The transcriptional activity of several Ets family members is regulated by Ras, and interfering with Ets-dependent transcription by expression of just the Ets2 DNA binding domain can inhibit or reverse Ras-mediated cellular transformation. To better understand the role of Ets proteins in Ras transformation, we have now analyzed the...

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Identifiers

PMID: 9668063
DOI: 10.1074/jbc.273.30.18871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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