Article
Formation of multivesicular endosomes in Dictyostelium.
Journal of cell science - 1 Dec 2004
Marchetti Anna, Mercanti Valentina, Cornillon Sophie, Alibaud Laeticia, Charette Steve J, Cosson Pierre
Abstract excerpt
Multivesicular endosomes are present in virtually every eucaryotic cell, where they arise by intra-endosomal budding of the limiting endosomal membrane. Some genetic diseases such as Chediak-Higashi syndrome are characterized by enlarged membrane-filled endosomes. The same altered endosomal morphology can be observed in cells exposed to certain drugs, for example U18666A. The mechanisms involved are still poorly...
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