Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autophagy contributes to degradation of Hirano bodies.

Autophagy - 1 Jan 2009

Kim Dong-Hwan, Davis Richard C, Furukawa Ruth, Fechheimer Marcus

Abstract excerpt

Hirano bodies are actin-rich inclusions reported most frequently in the hippocampus in association with a variety of conditions including neurodegenerative diseases, and aging. We have developed a model system for formation of Hirano bodies in Dictyostelium and cultured mammalian cells to permit detailed studies of the dynamics of these structures in living cells. Model Hirano bodies are frequently observed in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy
Share to Cell Compartmentation
Share to Dictyostelium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Exocytosis

Share to Inclusion Bodies

Share to Molecular Weight

Share to Proteasome Endopeptidase Complex

Share to Secretory Vesicles

Source

Open in PubMed Open full text

Identifiers

PMID: 18989098
DOI: 10.4161/auto.5.1.7228
PMCID: PMC2674366

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autophagy contributes to degradation of Hirano bodies.PMID 18989098Read ↗

Formation of Hirano bodies induced by expression of an actin cross-linking protein with a gain-of-function mutation.Semantic proximity Read ↗

The two Dictyostelium discoideum autophagy 8 proteins have distinct autophagic functions.Semantic proximity Read ↗

Autophagy Gene Disruption Reveals a Non-vacuolar Cell Death Pathway in DictyosteliumSemantic proximity Read ↗

Deficiency of huntingtin has pleiotropic effects in the social amoeba Dictyostelium discoideum.Semantic proximity Read ↗

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.Semantic proximity Read ↗

Functional Characterisation of the Autophagy ATG12~5/16 Complex in Dictyostelium discoideum.Semantic proximity Read ↗

Genetic suppressor of autophagy defects in huntingtin null cells identified using a mutagenesis screen in Dictyostelium discoideum.Semantic proximity Read ↗

Dictyostelium as a model for human lysosomal and trafficking diseases.Semantic proximity Read ↗

Formation of multivesicular endosomes in Dictyostelium.Semantic proximity Read ↗

Mroh1, a lysosomal regulator localized by WASH-generated actin.Semantic proximity Read ↗

Heteromeric p97/p97R155C Complexes Induce Dominant Negative Changes in Wild-Type and Autophagy 9-Deficient Dictyostelium strainsSemantic proximity Read ↗

Macroautophagy is required for multicellular development of the social amoeba Dictyostelium discoideum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.