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Article

Dictyostelium EHD associates with Dynamin and participates in phagosome maturation.

Journal of cell science - 15 Jun 2016

Gueho Aurélie, Bosmani Cristina, Gopaldass Navin, Molle Virginie, Soldati Thierry, Letourneur François

Abstract excerpt

Proteins that contain Eps15 homology domains (EHDs) in their C-terminus are newly identified key regulators of endosomal membrane trafficking. Here, we show that D. discoideum contains a single EHD protein (referred to as EHD) that localizes to endosomal compartments and newly formed phagosomes. We provide the first evidence that EHD regulates phagosome maturation. Deletion of EHD results in defects in...

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Identifiers

PMID: 27170354
DOI: 10.1242/jcs.182857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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