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Article

A LYST/beige homolog is involved in biogenesis of Dictyostelium secretory lysosomes.

Journal of cell science - 15 Jul 2007

Charette Steve J, Cosson Pierre

Abstract excerpt

Chediak-Higashi syndrome (CHS) is characterized at the cellular level by a defect in the ability of cells to secrete lysosomes. However, the precise step affected in the secretion process is unclear. We characterized Dictyostelium discoideum cells containing a mutation in lvsB, the homolog of the human gene (LYST) involved in CHS. As observed in mammalian cells, secretion of lysosome-derived compartments was...

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Source

Identifiers

PMID: 17606989
DOI: 10.1242/jcs.009001

Genes

LYST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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A LYST/beige homolog is involved in biogenesis of Dictyostelium secretory lysosomes.PMID 17606989Read ↗

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