Article
LvsA, a protein related to the mouse beige protein, is required for cytokinesis in Dictyostelium.
Molecular biology of the cell - 1 Dec 1999
Kwak E, Gerald N, Larochelle D A, Vithalani K K, Niswonger M L, Maready M, De Lozanne A
Abstract excerpt
We isolated a Dictyostelium cytokinesis mutant with a defect in a novel locus called large volume sphere A (lvsA). lvsA mutants exhibit an unusual phenotype when attempting to undergo cytokinesis in suspension culture. Early in cytokinesis, they initiate furrow formation with concomitant myosin II localization at the cleavage furrow. However, the furrow is later disrupted by a bulge that forms in the middle of...
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