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Article

Dictyostelium discoideum mutants with temperature-sensitive defects in endocytosis.

The Journal of cell biology - 1 Oct 1994

Bacon R A, Cohen C J, Lewin D A, Mellman I

Abstract excerpt

We have isolated and characterized temperature-sensitive endocytosis mutants in Dictyostelium discoideum. Dictyostelium is an attractive model for genetic studies of endocytosis because of its high rates of endocytosis, its reliance on endocytosis for nutrient uptake, and tractable molecular genetics. Endocytosis-defective mutants were isolated by a fluorescence-activated cell sorting (FACS) as cells unable to...

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Identifiers

PMID: 7929583
DOI: 10.1083/jcb.127.2.387
PMCID: PMC2120217

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