Dictyostelium discoideum mutants with temperature-sensitive defects in endocytosis.

doi:10.1083/jcb.127.2.387

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Article

Dictyostelium discoideum mutants with temperature-sensitive defects in endocytosis.

The Journal of cell biology - 1 Oct 1994

Bacon R A, Cohen C J, Lewin D A, Mellman I

Abstract excerpt

We have isolated and characterized temperature-sensitive endocytosis mutants in Dictyostelium discoideum. Dictyostelium is an attractive model for genetic studies of endocytosis because of its high rates of endocytosis, its reliance on endocytosis for nutrient uptake, and tractable molecular gene...

Topics

Adenosine Triphosphate
Animals
Biological Transport
Dictyostelium
Endocytosis
Fungal Proteins
Genes, Fungal
Lysosomes
Mannosidases
Membrane Proteins
Mutation
Phagocytosis
Phenotype
Temperature
Vacuoles
alpha-Mannosidase

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