Quality assessment and correlation of microsatellite instability and immunohistochemical markers among population- and clinic-based colorectal tumors results from the Colon Cancer Family Registry.

doi:10.1016/j.jmoldx.2010.12.004

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Article

Quality assessment and correlation of microsatellite instability and immunohistochemical markers among population- and clinic-based colorectal tumors results from the Colon Cancer Family Registry.

The Journal of molecular diagnostics : JMD - 1 May 2011

Cicek Mine S, Lindor Noralane M, Gallinger Steven, Bapat Bharati, Hopper John L, Jenkins Mark A, Young Joanne, Buchanan Daniel, Walsh Michael D, Le Marchand Loic, Burnett Terrilea, Newcomb Polly A, Grady William M, Haile Robert W, Casey Graham, Plummer Sarah J, Krumroy Lisa A, Baron John A, Thibodeau Stephen N

Abstract excerpt

The detection of defective mismatch repair (MMR), as assessed by the presence of tumor microsatellite instability (MSI) and/or loss of MMR protein expression by IHC, has been useful for risk assessment, prognosis, and prediction of treatment in patients with colorectal cancer. We analyzed tumors for the presence of defective MMR from 5927 Colorectal Cancer Family Registry patients recruited at six international...

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PMID: 21497289
DOI: 10.1016/j.jmoldx.2010.12.004
PMCID: PMC3077724

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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