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Article

MSI-testing in hereditary non-polyposis colorectal carcinoma (HNPCC).

Disease markers - 1 Jan 2004

Müller Annegret, Edmonston Tina Bocker, Dietmaier Wolfgang, Büttner Reinhard, Fishel Richard, Rüschoff Josef

Abstract excerpt

Genomic instability at simple repeated sequences, termed microsatellite instability (MSI), plays an important role in the analysis of sporadic and hereditary colon cancers. In hereditary non-polyposis colorectal cancer syndrome (HNPCC) more than 90% of cases show MSI, whereas only 10-15% of sporadic colorectal cancers do so. Thus, microsatellite analysis is commonly used as the first diagnostic screening test for...

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Identifiers

PMID: 15528788
DOI: 10.1155/2004/343976
PMCID: PMC3839272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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