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Article

Detection of microsatellite instability in colorectal cancer using an alternative multiplex assay of quasi-monomorphic mononucleotide markers.

The Journal of molecular diagnostics : JMD - 1 Mar 2008

Deschoolmeester Vanessa, Baay Marc, Wuyts Wim, Van Marck Eric, Van Damme Nancy, Vermeulen Peter, Lukaszuk Krzysztof, Lardon Filip, Vermorken Jan B

Abstract excerpt

Colorectal malignancies demonstrating microsatellite instability (MSI) have a very heterogeneous histological appearance, better prognosis, and altered response to therapy. Consequently, identification of the MSI phenotype is both relevant and interesting as a screening and prognostic tool and as a potential predictive factor of chemotherapeutic response. Several groups have argued for the exclusive use of...

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Source

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Identifiers

PMID: 18258928
DOI: 10.2353/jmoldx.2008.070087
PMCID: PMC2259470

Genes

MLH1
MSH2
MSH6
SEC63

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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