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Article

Beta-catenin and BMP-2 synergize to promote osteoblast differentiation and new bone formation.

Journal of cellular biochemistry - 1 Feb 2005

Mbalaviele Gabriel, Sheikh Sharmin, Stains Joseph P, Salazar Valerie S, Cheng Su-Li, Chen Di, Civitelli Roberto

Abstract excerpt

Mutations of critical components of the Wnt pathway profoundly affect skeletal development and maintenance, probably via modulation of beta-catenin signaling. We tested the hypothesis that beta-catenin is involved in mesenchymal lineage allocation to osteogenic cells using a beta-catenin mutant w...

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Identifiers

PMID: 15526274
DOI: 10.1002/jcb.20253
PMCID: PMC2647989

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15526274-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Beta-catenin and BMP-2 synergize to promote osteoblast differentiation and new bone formation.PMID 15526274Read ↗

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