Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development.

Developmental biology - 1 Sept 2012

van Amerongen Renée, Fuerer Christophe, Mizutani Makiko, Nusse Roel

Abstract excerpt

Embryonic development is controlled by a small set of signal transduction pathways, with vastly different phenotypic outcomes depending on the time and place of their recruitment. How the same molecular machinery can elicit such specific and distinct responses, remains one of the outstanding questions in developmental biology. Part of the answer may lie in the high inherent genetic complexity of these signaling...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcification, Physiologic
Share to Hair Follicle
Share to Osteogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Receptor Tyrosine Kinase-like Orphan Receptors

Share to Tetracycline

Share to Wnt-5a Protein

Share to Wnt Proteins

Share to Wnt Signaling Pathway

Source

Open in PubMed Open full text

Identifiers

PMID: 22771246
DOI: 10.1016/j.ydbio.2012.06.020
PMCID: PMC3435145

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development.PMID 22771246Read ↗

WNT-5A: signaling and functions in health and diseaseSemantic proximity Read ↗

Wnt5a is required for proper mammary gland development and TGF-β-mediated inhibition of ductal growthSemantic proximity Read ↗

Wnt signaling: a common theme in animal development.Semantic proximity Read ↗

WNT7A.Semantic proximity Read ↗

Expression and Function of WNT6: From Development to DiseaseSemantic proximity Read ↗

Impact of WNT signaling on tissue lineage differentiation in the early mouse embryo.Semantic proximity Read ↗

The opposing roles of Wnt-5a in cancerSemantic proximity Read ↗

Wnt signaling in disease and in development.Semantic proximity Read ↗

Knockout mouse models to study Wnt signal transduction.Semantic proximity Read ↗

Is Wnt5a overexpression sufficient for generating a psoriasis-like phenotype in transgenic mice?Semantic proximity Read ↗

Wnt5a gain- and loss-of-function present distinctly in craniofacial boneSemantic proximity Read ↗

Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.