Article

MiR-486-3p promotes osteogenic differentiation of BMSCs by targeting CTNNBIP1 and activating Wnt/β-catenin pathway

2021-04-07

Abstract excerpt

<title>Abstract</title> <p>Background Dysfunction in osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) leads to bone loss/osteoporosis. CTNNBIP1 (Catenin beta interacting protein 1) is an inhibitor of Wnt/β-catenin signaling, whose role in osteogenesis remains elusive. This study aims to reveal the effects of miR-486-3p/CTNNBIP1 in osteogenesis. Methods Bone marrow samples from control an...

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Literature Corpus work: 4e2484bf-6a12-5704-8276-ac55fdcfaf3f
DOI: 10.21203/rs.3.rs-396210/v1

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