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Cerebrospinal fluid beta-amyloid1-42 and tau in control subjects at risk for Alzheimer's disease: the effect of APOE epsilon4 allele.

Biological psychiatry - 1 Nov 2004

Sunderland Trey, Mirza Nadeem, Putnam Karen T, Linker Gary, Bhupali Deepa, Durham Rob, Soares Holly, Kimmel Lida, Friedman David, Bergeson Judy, Csako Gyorgy, Levy James A, Bartko John J, Cohen Robert M

Abstract excerpt

BACKGROUND: Cerebrospinal fluid (CSF) measures of beta-amyloid(1-42) and tau are linked with the known neuropathology of Alzheimer's disease (AD). Numerous lines of evidence have also suggested that individuals with at least one APOE epsilon4 allele on chromosome 19 are at increased risk of developing AD. We tested these CSF markers in groups of subjects with AD and healthy older control subjects, using the...

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Source

Identifiers

PMID: 15522251
DOI: 10.1016/j.biopsych.2004.07.021

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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