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Article

Stability of CSF beta-amyloid(1-42) and tau levels by APOE genotype in Alzheimer patients.

Dementia and geriatric cognitive disorders - 1 Jan 2006

Huey Edward D, Mirza Nadeem, Putnam Karen T, Soares Holly, Csako Gyorgy, Levy James A, Copenhaver Brittany, Cohen Robert M, Sunderland Trey

Abstract excerpt

BACKGROUND: Cerebrospinal fluid (CSF) measures of beta-amyloid(1-42 )and tau differ between patients with Alzheimer's Disease (AD) and elderly normal controls. The effect of time and APOE genotype on these biomarkers continues to be elucidated. METHODS: We assessed CSF beta-amyloid(1-42) and tau in 20 mild-to-moderate AD patients, 11 APOE epsilon4+ and 9 APOE epsilon4-, over a mean time of 3.8 years (range 1-11.1...

Topics

Aged
Alleles
Alzheimer Disease
Amyloid beta-Peptides
Apolipoproteins E
Biomarkers
Female
Genotype
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neuropsychological Tests

Peptide Fragments

tau Proteins

Source

Identifiers

PMID: 16682793
DOI: 10.1159/000093261

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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