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Article

CSF biomarkers in Alzheimer's disease and controls: associations with APOE genotype are modified by age.

Journal of Alzheimer's disease : JAD - 1 Jan 2009

Kester Maartje I, Blankenstein Marinus A, Bouwman Femke H, van Elk Evert J, Scheltens Philip, van der Flier Wiesje M

Abstract excerpt

The object of this study was to elucidate the effect of age in the relationship between APOE genotype and CSF biomarkers amyloid-beta1-42 (Abeta42), total tau (tau) and tau phosphorylated at threonine 181 (ptau-181) in AD and controls. 302 AD patients and 174 controls were categorized into APOE epsilon4 carriers and non-carriers, and into younger and older (65years). In controls, older age and APOE epsilon4 were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19276554
DOI: 10.3233/JAD-2009-0999

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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