Article
D1-like dopamine receptor-mediated function in congenic mutants with D1 vs. D5 receptor "knockout".
Journal of receptor and signal transduction research - 1 Aug 2004
O'Sullivan Gerard J, Clifford Jeremiah J, Tomiyama Katsunori, Koshikawa Noriaki, Drago John, Sibley David R, Croke David T, Waddington John L
Abstract excerpt
Current understanding of the functional roles of individual dopamine D1-like [D1, D5] and D2-like [D2L/s, D3, D4] receptor subtypes remains incomplete. In particular, the lack of pharmacological agonists and antagonists able to distinguish between D1 and D5 receptors means that any differential roles in the regulation of behavior are poorly understood. Mutant mice with targeted gene deletion ("knockout") of...
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