Article
Comparative, topographically-based evaluation of behavioural phenotype and specification of D(1)-like:D(2) interactions in a line of incipient congenic mice with D(2) dopamine receptor 'knockout'.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Oct 2001
Clifford J J, Kinsella A, Tighe O, Rubinstein M, Grandy D K, Low M J, Croke D T, Waddington J L
Abstract excerpt
Phenotypes were assessed topographically in mice lacking functional D(2) dopamine receptors ['knockouts'], using an ethologically based approach to assess all behaviours in the natural repertoire. D(2)-null mice evidenced an ethogram characterised initially by modest reductions in locomotion and shifts in rearing topographies. Subsequently, topographies of behaviour habituated similarly for wildtypes and...
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