Article
Phenotypic resolution of spontaneous and D1-like agonist-induced orofacial movement topographies in congenic dopamine D1A receptor 'knockout' mice.
Neuropharmacology - 1 Apr 2002
Tomiyama K, McNamara F N, Clifford J J, Kinsella A, Drago J, Tighe O, Croke D T, Koshikawa N, Waddington J L
Abstract excerpt
A novel system was used to assess the role of D(1)-like dopamine receptors in distinct topographies of orofacial movements in mice with congenic D(1A) receptor knockout. Under spontaneous conditions, vertical jaw movements in wild-types declined with time at a rate that was reduced in D(1A) mutants, while horizontal jaw movements emerged progressively in wild-types but not in D(1A) mutants; tongue protrusions...
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