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Article

Topographical Assessment of Ethological and Dopamine Receptor Agonist-Induced Behavioral Phenotype in Mutants with Congenic DARPP-32 'Knockout'.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Dec 2003

Nally Rachel E, McNamara Fergal N, Clifford Jeremiah J, Kinsella A, Tighe Orna, Croke David T, Fienberg Allen A, Greengard Paul, Waddington John L

Abstract excerpt

Congenic (10 backcrosses into C57BL/6J) mutants with targeted gene deletion of DARPP-32, a neuronal phosphoprotein regarded as an essential mediator of the biological effects of dopamine (DA), were assessed phenotypically using an ethologically based approach that resolves all topographies of beh...

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Identifiers

PMID: 12865890
DOI: 10.1038/sj.npp.1300259

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12865890-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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