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Article

Congenic D1A dopamine receptor mutants: ethologically based resolution of behavioural topography indicates genetic background as a determinant of knockout phenotype.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jan 2003

McNamara Fergal N, Clifford Jeremiah J, Tighe Orna, Kinsella Anthony, Drago John, Croke David T, Waddington John L

Abstract excerpt

D(1A)-null mice were backcrossed over 14 generations into a C57BL/6 background to result in essential elimination (to <0.005%) of any contribution from the 129/Sv component of their initially mixed (129/SvxC57BL/6) background. Their phenotype was assessed using an ethologically based approach that resolves each individual topography of behaviour in the natural repertoire. Habituation of sniffing, locomotion,...

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Identifiers

PMID: 12496944
DOI: 10.1038/sj.npp.1300008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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