Article
The role of caldesmon in the regulation of endothelial cytoskeleton and migration.
Journal of cellular physiology - 1 Jun 2005
Mirzapoiazova Tamara, Kolosova Irina A, Romer Lew, Garcia Joe G N, Verin Alexander D
Abstract excerpt
The actin- and myosin-binding protein, caldesmon (CaD) is an essential component of the cytoskeleton in smooth muscle and non-muscle cells and is involved in the regulation of cell contractility, division, and assembly of actin filaments. CaD is abundantly present in endothelial cells (EC); however, the contribution of CaD in endothelial cytoskeletal arrangement is unclear. To examine this contribution, we...
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