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Article

Maspin Regulates Endothelial Cell Adhesion and Migration through an Integrin Signaling Pathway

17 Aug 2010

Abstract excerpt

Maspin has been identified as a potent angiogenesis inhibitor. However, the molecular mechanism responsible for its anti-angiogenic property is unclear. In this study, we examined the effect of maspin on endothelial cell (EC) adhesion and migration in a cell culture system. We found that maspin was expressed in blood vessels ECs and human umbilical vein endothelial cells (HUVECs). Maspin significantly enhanced...

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PMID: 20713357
DOI: 10.1074/jbc.m110.131045

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