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Article

Classical photoreceptors regulate melanopsin mRNA levels in the rat retina.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 Oct 2004

Sakamoto Katsuhiko, Liu Cuimei, Tosini Gianluca

Abstract excerpt

Recent studies have demonstrated that melanopsin is a key photopigment in the mammalian circadian system. This novel opsin is exclusively expressed in retinal ganglion cells that are intrinsically sensitive to light, perhaps responding via a melanopsin-based signaling pathway. Previous investigations using transgenic mice have also demonstrated that ablation of the classical photoreceptors and of melanopsin...

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Identifiers

PMID: 15509757
DOI: 10.1523/JNEUROSCI.2556-04.2004
PMCID: PMC6730153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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