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Article

Influence of eye pigmentation on retinal degeneration in P23H and S334ter mutant rhodopsin transgenic rats.

Experimental eye research - 1 Oct 2019

Lowe Robert J, Daniello Kate M, Duncan Jacque L, Yang Haidong, Yasumura Douglas, Matthes Michael T, LaVail Matthew M

Abstract excerpt

Dark-rearing has been found to slow the rate of retinal degeneration in albino P23H but not S334ter mutant rhodopsin transgenic (Tg) rats. Since eye pigmentation has the same protective slowing effect as dark-rearing in RCS rats, we examined whether eye pigmentation has a comparable slowing effect in the different mutant rhodopsin Tg rats. Different lines of albino P23H and S334ter Tg rats on the Sprague-Dawley...

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Source

Identifiers

PMID: 31408630
DOI: 10.1016/j.exer.2019.107755

Genes

ERG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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