Article
Genetic, age and light mediated effects on crystallin protein expression in the retina.
Photochemistry and photobiology - 1 Jan 2000
Organisciak Daniel, Darrow Ruth, Gu Xiaorong, Barsalou Linda, Crabb John W
Abstract excerpt
To probe for possible relationships between retinal crystallins and retinal degenerations, protein expression was compared in normal Sprague-Dawley rats, treated or not with intense light, Royal College of Surgeons (RCS) rats and transgenic rats expressing rhodopsin mutations. Rats were reared in dim cyclic light for 21-75 days. Photoreceptor cell DNA levels were determined at various ages to assess the rates of...
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