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Article

Effect of photoreceptor degeneration on circadian photoreception and free-running period in the Royal College of Surgeons rat.

Brain research - 7 May 2007

Tosini Gianluca, Aguzzi Jacopo, Bullock Nicole M, Liu Cuimei, Kasamatsu Manami

Abstract excerpt

The study of how the retina processes the photic information required for the entrainment of the circadian system is an exciting new topic in retinal neurobiology. We have recently shown that in RCS/N-rdy rats melanopsin mRNA levels are dramatically reduced (about 90%) and melanopsin immunoreactivity cannot be detected in the retina of these rats at 60 days of age. Although RCS/N-rdy rats are a widely used model...

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Identifiers

PMID: 17382912
DOI: 10.1016/j.brainres.2007.02.055
PMCID: PMC1939936

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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