Article
Scores of asthma and asthma severity reveal new regions of linkage in EGEA study families.
The European respiratory journal - 1 Aug 2007
Bouzigon E, Siroux V, Dizier M-H, Lemainque A, Pison C, Lathrop M, Kauffmann F, Demenais F, Pin I
Abstract excerpt
There is ongoing debate as to how asthma should be defined in order to forward understanding of the underlying mechanisms. The aim of the present study was to build quantitative scores of asthma and asthma severity and to assess whether refinement of disease phenotypes can facilitate the identification of chromosomal regions harbouring susceptibility genes. A genome-wide linkage scan was conducted in 110 families...
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