Article
Apolipoprotein E genotyping: accurate, simple, high throughput method using ABI Prism SNaPshot Multiplex System.
Journal of Alzheimer's disease : JAD - 1 Oct 2004
Ben-Avi Liat, Durst Ronen, Shpitzen Shoshi, Leitersdorf Eran, Meiner Vardiella
Abstract excerpt
Apolipoprotein E (apo E) is an essential constituent of several plasma lipoproteins, and plays an important role in lipoprotein metabolism. The apo E gene exhibits two common functional polymorphisms, producing 3 isoforms known to be associated with the risks of developing cardiovascular disease and susceptibility to Alzheimer's disease. Numerous different methods have been established for determining the three...
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