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Article

A rapid and cost-effective method for genotyping apolipoprotein E gene polymorphism.

Molecular neurodegeneration - 12 Jan 2016

Zhong Li, Xie Yong-Zhuang, Cao Tian-Tian, Wang Zongqi, Wang Tingting, Li Xinxiu, Shen Rui-Chi, Xu Huaxi, Bu Guojun, Chen Xiao-Fen

Abstract excerpt

BACKGROUND: Apolipoprotein E (ApoE) is a major cholesterol carrier and plays an important role in maintaining lipid homeostasis both in the periphery and brain. Human APOE gene is polymorphic at two single nucleotides (rs429358 and rs7412) resulting in three different alleles (ε2, ε3 and ε4). ApoE isoforms modulate the risk for a variety of vascular and neurodegenerative diseases; thus, APOE genotyping is crucial...

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Source

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Identifiers

PMID: 26754117
DOI: 10.1186/s13024-016-0069-4
PMCID: PMC4710020

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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