Article
Genotyping of apolipoprotein E: comparative evaluation of different protocols.
Current protocols in human genetics - 1 Nov 2003
Ingelsson Martin, Shin Youngah, Irizarry Michael C, Hyman Bradley T, Lilius Lena, Forsell Charlotte, Graff Caroline
Abstract excerpt
Disease-associated gene polymorphisms provide both scientific insight into pathophysiological mechanisms and clinical information regarding risk and progression. Of special interest is the epsilon4 allele of the apolipoprotein E gene, which has emerged as a substantial risk factor for late-onset forms of Alzheimer disease and also influences the risk of cardiovascular disease. Genotyping of apolipoprotein E can...
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