A multilocus extension of the affected-pedigree-member method of linkage analysis.

Article

A multilocus extension of the affected-pedigree-member method of linkage analysis.

American journal of human genetics - 1 Apr 1992

Weeks D E, Lange K

Abstract excerpt

The affected-pedigree-member (APM) method of linkage analysis is designed to detect departures from independent segregation of disease and marker phenotypes. The underlying statistic of the APM method operates on the identity-by-state relations implied by the marker phenotypes of the affected wit...

Topics

Genetic Linkage
Genetic Markers
Genetic Techniques
Genotype
Humans
Pedigree

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