The power of identity-by-state methods for linkage analysis.

Article

The power of identity-by-state methods for linkage analysis.

American journal of human genetics - 1 Feb 1990

Bishop D T, Williamson J A

Abstract excerpt

The affected-sib-pair method has been widely utilized for mapping. This methodology is aimed at mapping complex traits which have been observed to be familial but for which Mendelian segregation, even after allowing for partial penetrance, is not apparent. Indications of linkage are based on the...

Topics

Female
Genetic Linkage
Genetics, Medical
Humans
Male
Mathematics
Models, Genetic
Models, Statistical
Pedigree
Phenotype
Probability

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