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Article

Improved programs for the affected-pedigree-member method of linkage analysis.

Genetic epidemiology - 1 Jan 1994

Schroeder M, Brown D L, Weeks D E

Abstract excerpt

The affected-pedigree-member (APM) method is a non-parametric method of linkage analysis, which requires no assumptions about how the trait of interest is inherited [Weeks and Lange, 1988, 1991, 1992; Lange and Weeks, 1990; Weeks et al., 1992]. The APM method uses only the affected members of each pedigree who are typed for the marker(s). Based on the affected members' marker genotypes and the relationships of...

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PMID: 8013889
DOI: 10.1002/gepi.1370110107

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