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Article

Improved programs for the affected-pedigree-member method of linkage analysis.

Genetic epidemiology - 1 Jan 1994

Schroeder M, Brown D L, Weeks D E

Abstract excerpt

The affected-pedigree-member (APM) method is a non-parametric method of linkage analysis, which requires no assumptions about how the trait of interest is inherited [Weeks and Lange, 1988, 1991, 1992; Lange and Weeks, 1990; Weeks et al., 1992]. The APM method uses only the affected members of each pedigree who are typed for the marker(s). Based on the affected members' marker genotypes and the relationships of...

Topics

Bias
Chromosome Mapping
Evaluation Studies as Topic
Genetic Markers
Genotype
Humans
Models, Genetic
Pedigree
Recombination, Genetic
Reproducibility of Results
Software Validation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8013889
DOI: 10.1002/gepi.1370110107

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8013889-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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