Article
Nonparametric simulation based linkage statistics for general pedigrees.
The Journal of rheumatology - 1 Jan 1997
Weeks D E, Davis S, Schroeder M, Goldin L R
Abstract excerpt
A common strategy for testing for linkage without posing a disease model is to test for increased marker similarity among the affected pedigree members. We developed a simulation based statistic, SimIBD, which measures marker similarity in terms of identity-by-descent (IBD) when it can be determined whether or not the alleles are IBD, and in terms of the probability of the alleles being IBD when it cannot be...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.