Article
Mammalian protein SCP1 forms synaptonemal complex-like structures in the absence of meiotic chromosomes.
Molecular biology of the cell - 1 Jan 2005
Ollinger Rupert, Alsheimer Manfred, Benavente Ricardo
Abstract excerpt
Synaptonemal complexes (SCs) are evolutionary conserved, meiosis-specific structures that play a central role in synapsis of homologous chromosomes, chiasmata distribution, and chromosome segregation. However, it is still for the most part unclear how SCs do assemble during meiotic prophase. Major components of mammalian SCs are the meiosis-specific proteins SCP1, 2, and 3. To investigate the role of SCP1 in SC...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
