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Article

SYCE2 is required for synaptonemal complex assembly, double strand break repair, and homologous recombination.

The Journal of cell biology - 12 Mar 2007

Bolcun-Filas Ewelina, Costa Yael, Speed Robert, Taggart Mary, Benavente Ricardo, De Rooij Dirk G, Cooke Howard J

Abstract excerpt

Synapsis is the process by which paired chromosome homologues closely associate in meiosis before crossover. In the synaptonemal complex (SC), axial elements of each homologue connect through molecules of SYCP1 to the central element, which contains the proteins SYCE1 and -2. We have derived mice lacking SYCE2 protein, producing males and females in which meiotic chromosomes align and axes form but do not...

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Source

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Identifiers

PMID: 17339376
DOI: 10.1083/jcb.200610027
PMCID: PMC2064047

Genes

SYCP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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SYCE2 is required for synaptonemal complex assembly, double strand break repair, and homologous recombination.PMID 17339376Read ↗

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