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Article

BMP receptor signaling is required for postnatal maintenance of articular cartilage.

PLoS biology - 1 Nov 2004

Rountree Ryan B, Schoor Michael, Chen Hao, Marks Melissa E, Harley Vincent, Mishina Yuji, Kingsley David M

Abstract excerpt

Articular cartilage plays an essential role in health and mobility, but is frequently damaged or lost in millions of people that develop arthritis. The molecular mechanisms that create and maintain this thin layer of cartilage that covers the surface of bones in joint regions are poorly understood, in part because tools to manipulate gene expression specifically in this tissue have not been available. Here we use...

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Share to Bone Morphogenetic Protein Receptors, Type I
Share to Cartilage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cartilage, Articular

Share to Chromosomes, Artificial, Bacterial

Share to Growth Differentiation Factor 5

Share to Joints

Share to Osteoarthritis

Share to Synovial Membrane

Source

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Identifiers

PMID: 15492776
DOI: 10.1371/journal.pbio.0020355
PMCID: PMC523229

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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