Article
Functional effects of susceptibility genes in osteoarthritis.
Discovery medicine - 1 Aug 2011
Cornelis Frederique M F, Luyten Frank P, Lories Rik J
Abstract excerpt
Osteoarthritis is the most common chronic musculoskeletal disorder. Although osteoarthritis is a multifactorial disease, it is known to have a significant genetic contribution. Identified genes so far, contributing to the prevalence and progression of the disease, belong to signaling pathways such as the bone morphogenetic protein and the wingless-type signaling families. These pathways are important during...
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