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Article

The Role of Bmp2 in the Maturation and Maintenance of the Murine Knee Joint.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Sept 2018

Gamer Laura W, Pregizer Steven, Gamer Jackson, Feigenson Marina, Ionescu Andreia, Li Qing, Han Lin, Rosen Vicki

Abstract excerpt

Bone morphogenetic proteins (BMPs) are key regulators of skeletal development, growth, and repair. Although BMP signaling is required for synovial joint formation and is also involved in preserving joint function after birth, the role of specific BMP ligands in adult joint homeostasis remains unclear. The purpose of this study was to define the role of Bmp2 in the morphogenesis and maintenance of the knee joint....

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PMID: 29665134
DOI: 10.1002/jbmr.3441

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AFM

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