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Article

Joint patterning defects caused by single and double mutations in members of the bone morphogenetic protein (BMP) family.

Development (Cambridge, England) - 1 Dec 1996

Storm E E, Kingsley D M

Abstract excerpt

The mouse brachypodism locus encodes a bone morphogenetic protein (BMP)-like molecule called growth/differentiation factor 5 (GDF5). Here we show that Gdf5 transcripts are expressed in a striking pattern of transverse stripes within many skeletal precursors in the developing limb. The number, location and time of appearance of these stripes corresponds to the sites where joints will later form between skeletal...

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Source

Identifiers

PMID: 9012517
DOI: 10.1242/dev.122.12.3969

Genes

GDF5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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